Although malaria ( 疟疾 ) deaths have fallen worldwide over the last decade,health leaders warned of a small but rising threat in parts of Southeast Asia, where anti-malaria drug resistance is confusing 1. Four countries--Cambodia, Myanmar, Thailandand Vietnam--make up an "epicenter to malarial drug resistance," said Robert Newman,the2of the World Health Organization's Global Malaria Program.
    Researchers have found that people in the Southeast Asia region have 3 highrates of resistance to artemisinin-based ( 以青蒿素为基础的 ) combination therapies,which are considered the best ways to treat the most deadly of the four types of parasitesthat 4 malaria in humans. It's a problem without a clear fix, even though malariadeaths in those countries have continued to5, he said.
    The cases represent only a tiny portion of malaria cases worldwide, but neverthelessrequire "more attention because history has taught us what happens if these cases get outof control," Newman said. Keeping drug resistance from 6 Africa is also critical, headded.
    The transmission of malaria across borders could be a factor. Insufficient regulationand inappropriate use of drugs also7, Newman said, giving the example ofpatients who stop using the medication after a few days because they start to feel better.
    Substandard or counterfeit ( 假冒的 ) medicines may play a role because they containenough of the right 8 to kill some of the infectious parasites, but not enough to killother bad strains.
    Drug resistance was a small but9 part of the World Health Organization's 2013 World Malaria Report. Global leaders in combating malaria identified problems in testingand reporting accurate estimates, but said that a lack of funding was the single greatestthreat to10eradicating malaria. 
A．accurately   
B．appropriate   
C．cause    
D．contribute  
E．decline 
F．director 
G．eventually 
H．experts 
I．ingredients 
J．patients 
K．perplexing 
L．reaching 
M．resistance 
N. St surprisingly 
O．treating